Cell Line Development Scientist ??? CMC

South East England
35000.00 - 45000.00 GBP Annual + GBP35000 - GBP45000/annum Depending on Skills and Experience
10 Feb 2017
25 Feb 2017
Contract Type
Full Time
Cell Line Development Scientist - CMC
Ref: 19426

Our client is a leading biopharmaceutical company focused on the discovery and development of fully human monoclonal antibody drugs using its proprietary antibody platform.

They are looking for an experienced laboratory-based senior scientist to develop our in-house commercial cell line development capabilities.

• To develop and optimise a mammalian expression platform to produce commercially relevant recombinant proteins e.g. antibodies cell lines
• Evaluating and implementing and troubleshooting new technologies including high-throughput automated cell culture systems
• Developing high throughput analytical technologies (Octet, icIEF, cSDS, etc.)
• Molecular biology and cell cloning
• Authoring of or relevant sections of regulatory submissions
• Contribute and lead on-going process development within the group
• Clear and accurate record keeping

• PhD or equivalent in cell or molecular biology/biotechnology
• Significant relevant experience in commercial cell line development for recombinant protein expression
• Ability to devise strategies to optimise expression
• A high level of motivation, innovative thinking, flexibility to adapt quickly and a "can do" attitude
• Ability to work to tight timelines, process several projects simultaneously and link effectively with project leaders and other scientists as required
• Automated data capture, analysis and visualisation
• Experienced in small scale protein purification
• Line management or matrix team leadership
• Experienced in regulatory submissions process
• Tech transfer experience

Role: Permanent
Location: East Anglia
Salary: Negotiable