Research Associate/ Senior Research Associate in Population Genetics a
Research Associate/ Senior Research Associate in Population Genetics and Epidemiology
Job number: ACAD102710
Division/School: School of Social and Community Medicine
Contract type: Open ended contract staff
Working pattern: Full time
Salary: Grade I: GBP32,004 - GBP36,001 per annum/ Grade J: GBP32,004 - GBP36,001 per annum.
Research Associate/Senior Research Associate in Population Genetics and Epidemiology
We are seeking a talented individual to develop new methodology for population demography and its relationship to phenotype and disease, working within MRC Integrative Epidemiology Unit (IEU) at the University of Bristol, working with Dr Daniel Lawson in the School of Social and Community Medicine and the Department of Statistics.
This research involves working on the border of genetics and epidemiology to develop new methods for understanding human genetics and phenotype data. You will develop new methods to detect, understand and exploit population structure in the context of selection and functional properties of genes. Populations for which we have data are growing in both scale and worldwide diversity coverage. This work will focus on using the genetic history of populations to learn things of biological and epidemiological relevance. The approach will involve population genetics, potentially utilising recent advances in fine-scale population structure detection using chromosome painting; see for example Leslie et al 2015 Nature 519:309-314.
Exploitation of such tools in an epidemiological setting is the goal for this post. The focus will primarily be targeted to GWAS, causal inference via Mandelian Randomization, or selection. The structure of intermediate phenotypes such as methylation, metabolites and other 'omic data is also of interest, where these are available for multiple genetically diverse cohorts and hence examinable from the perspective of population genetics.
To apply, please click on the Apply button to be redirected to our website, enter the vacancy number into the job search and follow the link to the online application process.
Closing date for applications: 23-Jul-2017.
Name, tel no and email details for informal contact/s: Daniel Lawson
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