Laboratory Research Scientist- Peptide Chemistry STP
This role is for Laboratory Research Scientist to provide temporary support to the Peptide Chemistry Science Technology Platform at the Crick. The Peptide Chemistry STP provides peptides, peptide arrays and small molecules to Crick scientists. This role will report to the STP lead, Nicola O'Reilly.
The main purpose of the Laboratory Research Scientist (Fixed Term) role in the Peptide Chemistry STP is to support this very busy STP in performing chemical synthesis (both using automated equipment and manually) and purification to generate peptides for experiments performed by scientists at the Crick. You will work as part of a team, working with other team members to get the work done as effectively as possible. You will also be responsible for maintaining good records of your work and for keeping working areas clean, tidy and safe.
These include but not limited to;
- Weighing out amino acids for use on the peptide synthesisers.
- To aid in maintenance of stocks, ordering of consumables, checking and unpacking of goods.
- To aid in chemical waste handling
- Synthesis of peptides using both automated peptide synthesisers and manual procedures.
- Cleavage of peptides from resin supports.
- Analysis of peptides by HPLC and mass spectrometry.
- Purification of peptides by HPLC.
- Maintaining paper and computer records of work carried out.
- To aid in equipment maintenance and liaison with manufacturers' service teams to ensure that all equipment is fully functional.
- General lab duties including keeping working area clean, tidy and safe
The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.
An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King's College London.
The Crick was formed in 2015, and in 2016 it moved into a brand new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under a single roof in Europe.
The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; to developing emerging talent and exporting it the rest of the UK; to public engagement; and to helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.
KEY EXPERIENCE AND COMPETENCIES
The post holder should embody and demonstrate our core Crick values: Bold, Imaginative, Open, Dynamic and Collegial, in addition to the following:
- BSc degree or equivalent in chemistry
- Previous experience of handling organic solvents and corrosive chemicals
- Candidates need a proven ability to think practically and solve problems
- Good organisational skills and attention to detail, with the ability to prioritise own workload
- Self-motivated with the ability to work both independently and as a team member
- Excellent inter-personal skills and a willingness to learn
- Intermediate computer skills
- Previous work experience in a laboratory would be advantageous
- Knowledge of peptide chemistry and HPLC would be advantageous